Pericyte Image Batch Processing (ver 1.2)

designed by Ryan Wang from Dr. Ke Yuan lab in Boston Children's Hospital

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📖 How to Use This App

This application uses AI (YOLO) to detect and analyze cells in microscopy images. To ensure the app works correctly, your files must follow the naming conventions described below.

1. File Naming Rules (Critical)

The app identifies the imaging channel based on the filename. You must use a separator (underscore _, dash -, or space) before the channel indicator.

Channel Format: Use ch# or ch## where # is a digit (0-9).

Grouping: Files with the same prefix (base name) are grouped together as one sample.
Example: S1_ch0.tif and S1_ch1.tif are processed together, or S1_ch00.tif and S1_ch01.tif.

2. Species Specifics

🧑 Human Cells

  • Supported Channels: ch00, ch01, ch02, ch03
  • Typical Mapping:
    • _ch00: Smooth muscle
    • _ch01: Pericyte
    • _ch02: Fibrolast C
    • _ch03: DAPI (Nuclei)
  • Overlay: Select which channels to overlay onto DAPI (ch03) using the dropdown menu.

🐭 Mouse Cells

  • Supported Channels: ch00, ch01
  • Typical Mapping:
    • _ch00: Pericyte
    • _ch01: Nuclei/DAPI
  • Special Rule: If a filename contains dapi (case-insensitive), it is automatically treated as Channel 1.

3. Automatic Channel Remapping (Human Cells)

Smart Detection: If you upload human cell images with only channels 0, 1, and 2 (missing channel 3), the app will automatically remap them:

This ensures your images are processed with the correct models even if you named them starting from 0.

4. Uploading & Processing